Insilico evaluation of pharmacological activities of Kalarchi Chooranam
نویسندگان
چکیده
The Indian traditional medicine practices such as siddha and ayurveda records various medicinal plants for the betterment of human health. Recent reports shows that this system has potential formulation to treat diseases ailments. In present study, we extracted prepared Kalarchi Chooranam ratios chosen 4:1 ratio from our previous work. aqueous extract was subjected GCMS study compounds Inositol, Xanthosine (CAS), alpha.-D-Glucopyranoside, methyl 2,3-bis-O- were identified lead 3 compounds. have passed drug likeness ADME properties further docked against receptors involved in disease pathogenesis cancer (Bcl2, Bcl-X), PCOS (Cyp17, Follistatin), Inflammation & Analgesic (Cox1, Cox2), Diabetics Cardiovascular (Er Alpha, Er Beta). overall reveals more binding affinities poly cystic ovarian syndrome showed significant energies -8.9 -8.2 Kcal/mol Alpha.-D-Glucopyranoside, 2,3-bis-O -9.7 CYP17 Follistatin. be studied reveal all its pharmacological activities.
منابع مشابه
evaluation of sadr eminence in safavid period
چکیده: یکی از دوره های مهم تاریخی ایران به لحاظ تأمین استقلال ملی مذهبی و حتی تأثیر آن بر فرهنگ و مذهب ایرانیان، دوره صفویه است. رسمیت دادن و رواج مذهب شیعه توسط شاه اسماعیل اول، یکی از مهمترین اقدامات این دولت محسوب می شود. بنابراین برای اجرای این سیاست، وی منصب صدارت را به عنوان منصبی مذهبی- حکو متی ایجاد کرد .این منصب از دوره ی تیموریان ایجاد شده بود ولی در اواخر این دوره اهمیت بیشتری یافت...
15 صفحه اولEvaluation of Pharmacological Activities of Leaves and Bark of Myristica fatua var. magnifica Extracts
Myristica fatua var. magnifica (Beddome) Sinclair belongs to the family Myristicaceae. It is a tree used as an important plant to cure various diseases. In the present study the Petroleum ether, Ethyl acetate and Methanolic extracts of Myristica fatua was evaluated for its toxicity, potential analgesic, depressant and in vitro and in vivo anti-inflammatory activity. The extracts at different co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Ayurvedic Medicine
سال: 2023
ISSN: ['0976-5921']
DOI: https://doi.org/10.47552/ijam.v13i4.3119